| Slimed! Demo (ver. 0.3) | Creator | |
| 94 |
| SmallGame (ver. 1.1) | hayashi ◪ | 2007-10-12 |
| 65 |
| Smash Time | Castlevania ◪ | |
| 188 |
| Smiley Fighter | Ben Sargo | |
| 83 |
| Smiley Knights | Triterra | |
| 64 |
| Smiley RPG | Mallo | 1997-12-23 |
| 197 |
| Smiley Wars Test | GetDizzy ◪ | 2004-06-10 |
| 64 |
| SMZX Tetris | Akwende ◪ | | No reviews. | 94 |
| Snake Slayer 2013 (ver. 1.1) | KKairos ◪ | 2013-12-26 |
| 131 |
| Snakes 2000 | Alan Iversen | |
| 67 |
| Snarfoogle | cheezit200 ◪ | |
| 277 |
| Snarfoogle 2: Warp (ver. Demo 2) | cheezit200 ◪ | |
| 135 |
| Snowman Smash | Triterra | |
| 61 |
| Some | RakiSoft | |
| 72 |
| Some Stupid Quests (ver. 2) | Kuddy ◪ | 2010-01-15 |
| 88 |
| Sonic Jam (ver. 0.8) | Zdrmonster1 ◪ | 2021-11-30 |
| 106 |
| Sonic's Quest | Sonic64 | |
| 80 |
| South Park Demo | Stewart Fullerton & James Greenwood | |
| 70 |
| Space Battles | Bugspray | |
| 65 |
| Space Station (demo) | Sonic1126 ◪ | 2000-03-29 |
| 69 |
| Space Station 2: Planetary Warp (demo) | Sonic1126 ◪ | 2000-08-21 |
| 79 |
| Spaceman Jones in: Ordeal on Glaxnard XIV (ver. 1.85) | KKairos ◪ | 2014-01-24 |
| 169 |
| SPECIAL QUEST! | Kuddy ◪ | 2005-04-01 |
| 151 |
| SpellWeavre | SpellWeavre ◪ | 1997-01-19 | No reviews. | 26 |
| Spirit Quest (ver. 2.0) | ThDPro ◪ | 2012-07-24 | No reviews. | 110 |
| Spirit Revenge (ver. 1.0.9703) | yenrab | 1997-03-23 |
| 356 |
| Spoder Road | Nemesis^ | 1997-07-23 |
| 79 |
| Spongko's Legendary Journey Demo | Eon Entertainment | |
| 188 |
| Spooky Boi | LogiCow ◪ | 2020-10-10 | No reviews. | 65 |
| Sprite Catcher | Nanobot ◪ | 2002-09-29 |
| 71 |
| Spy Guy | Aeon17 ◪ | |
| 70 |
| Spy Guy 2 | Aeon17 ◪ | |
| 68 |
| Squirm Wars 2 (Demo) | T-Bone ◪ | 2006-06-17 |
| 71 |
| Stafen War, The (Unfinished) | Chaos88 ◪ | 2015-08-14 | No reviews. | 55 |
| Stair Dismount | Slinky ◪ | |
| 62 |
| STAN | hob nado ◪ | 2008-01-08 |
| 73 |
| Star Trip | Thundercloud ◪ | |
| 65 |
| Star Wars | Joshua Booth | |
| 76 |
| Star Wars: Coruscant | KidAlex | |
| 59 |
| Starfighters | Xzavier R | |
| 79 |
| Starflight MZX (Project Dump) | Risu2112 ◪ | 2019-01-28 | No reviews. | 87 |
| Starflight Mzx Combat Demo (ver. 1.52) | Risu2112 ◪ | 2019-01-13 | No reviews. | 71 |
| Starforce: Space Adventure | MegaKev | |
| 72 |
| Stealth Boy Demo | Fighter_Phil ◪ | 2005-03-15 |
| 61 |
| Stemilt | Bramble ◪ | 2005-12-13 |
| 62 |
| Stix Demo (ver. 2) | Glynth | 1999-10-21 | No reviews. | 75 |
| Stolen Zambooboo Demo, The (ver. 1.2) | Brandon Faegre | 1996-11-27 |
| 56 |
| Stones and Roks (ver. 1.3) | zombieguy ◪ | 2003-11-01 | No reviews. | 80 |
| Stones and Roks II | zombieguy ◪ | 2003-05-03 |
| 83 |
| Stronghold Demo | Jauhis ◪ | 2010-01-31 |
| 147 |
